CONDITIONS

Skin Cancer: Reading Moles and Protecting Your Skin

Skin cancer ranges from highly treatable non-melanoma types to melanoma, which spreads more readily but is very treatable when caught early. Knowing the ABCDE warning signs helps catch it in time.

Updated 2026-08-205 min read2 cited sourcesEducational — not medical advice

Illustrative — skin, where changing moles deserve a check

In short

Skin cancer ranges from highly treatable non-melanoma types to melanoma, which spreads more readily but is very treatable when caught early. Knowing the ABCDE warning signs helps catch it in time.

On this page

01

Melanoma vs. Non-Melanoma Skin Cancer

Basal cell and squamous cell carcinomas, together called non-melanoma skin cancers, are the most common skin cancers and rarely spread beyond the skin, though they can grow locally and cause damage if untreated. Melanoma, arising from pigment-producing cells, is less common but more likely to spread to other organs if not caught early, making early recognition especially important.

02

Who Is at Risk

Cumulative sun exposure and a history of sunburns, especially earlier in life, raise risk for all skin cancer types, as does using tanning beds. Fair skin, many moles, a family history of melanoma, and a weakened immune system further increase risk, though skin cancer can occur in people with any skin tone.

03

The ABCDE Warning Signs

A simple way to check moles: Asymmetry, where one half doesn't match the other; Border irregularity; Color that varies within the same spot; Diameter larger than a pencil eraser; and Evolving, meaning any change in size, shape, or color over time. A new or changing spot, or a sore that doesn't heal, deserves a dermatologist's evaluation.

04

Diagnosis

A dermatologist examines suspicious spots, sometimes with a magnifying dermatoscope, and takes a biopsy of any concerning lesion to confirm the diagnosis under a microscope. For melanoma, the biopsy also measures how deeply the cancer has grown into the skin, which is the single biggest factor in staging and guiding treatment decisions.

05

Treatment Landscape and Outlook

Most non-melanoma skin cancers are removed with a simple in-office procedure and rarely return once excised. Melanoma caught early is treated primarily with surgical removal and has an excellent outlook; more advanced melanoma may involve immunotherapy or targeted drugs that have substantially improved outcomes in recent years. Daily sun protection — sunscreen, protective clothing, and shade — combined with annual skin checks for those at higher risk, remains the most effective way to lower risk going forward.

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